听力与言语-语言病理学

行为科学

医学伦理学

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  • Electrophysiological properties of developing phrenic motoneurons in the cat.

    abstract::1. Intracellular recordings were made in 427 phrenic motoneurons from kittens (in four stages of postnatal development, ranging from 2 to 14 wk) and in 72 motoneurons from adult cats. These experiments were performed to determine how the pattern of spontaneous discharge changes in phrenic motoneurons during developmen...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1991.65.3.671

    authors: Cameron WE,Jodkowski JS,Fang H,Guthrie RD

    更新日期:1991-03-01 00:00:00

  • Inhibition of lobster olfactory receptor cells by an odor-activated potassium conductance.

    abstract::1. Whole cell current-clamp recordings show that odors not only depolarize but may also hyperpolarize lobster olfactory receptor cells. Odor-evoked hyperpolarizations occurred in 36% of 178 receptor cells examined. Cell-attached recordings of action potentials followed by current-clamp recordings in the same cell indi...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1991.65.3.446

    authors: Michel WC,McClintock TS,Ache BW

    更新日期:1991-03-01 00:00:00

  • Physiological properties of neurons in the mouse superior olive: membrane characteristics and postsynaptic responses studied in vitro.

    abstract::1. The physiological properties of cells in the superior olivary complex (SOC) were studied in 400-microns brain slices taken through the mouse auditory brain stem. Coronal sections were prepared from fresh brain tissue and were placed fully submerged in an oxygenated saline solution. The boundaries of the medial nucl...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1991.65.2.230

    authors: Wu SH,Kelly JB

    更新日期:1991-02-01 00:00:00

  • Characteristics of midbrain control of spinal nociceptive neurons and nonsomatosensory parameters in the pentobarbital-anesthetized rat.

    abstract::1. GABAergic mechanisms in the midbrain periaqueductal gray (PAG) have been proposed to control the activity of descending antinociceptive systems and defensive behavior. Here, the effect of neuronal disinhibition by gamma-aminobutyric acid (GABAA) receptor blockade at midbrain sites on spinal neuronal responses to no...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1991.65.1.33

    authors: Sandkühler J,Willmann E,Fu QG

    更新日期:1991-01-01 00:00:00

  • Combined eye-head gaze shifts in the primate. III. Contributions to the accuracy of gaze saccades.

    abstract::1. The behavior of the combined eye-head gaze saccade mechanism was investigated in the rhesus monkey under both normal circumstances and in the presence of perturbations delivered to the head by a torque motor. Animals were trained to follow a target light that stepped at regular intervals through an angle of 68 degr...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.64.6.1873

    authors: Tomlinson RD

    更新日期:1990-12-01 00:00:00

  • Effects of tetanic contraction of motor units of similar type on the initial stiffness to ramp stretch of the cat peroneus longus muscle.

    abstract::1. The stiffness during the initial portion of a ramp stretch was measured in cat peroneus longus muscle at rest and during maximal tetanic contractions produced by increasing numbers of motor units of the same type [slow (S), fast fatigue resistant (FR), or fast fatigable (FF)]. 2. This initial ramp stiffness was def...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.64.6.1724

    authors: Petit J,Filippi GM,Gioux M,Hunt CC,Laporte Y

    更新日期:1990-12-01 00:00:00

  • Neuronal responsiveness in the ventrobasal thalamic complex of rats with an experimental peripheral mononeuropathy.

    abstract::1. Single-unit recordings were made, under moderate gaseous anesthesia (33% O2-66% N2O + 0.5/0.6% halothane), in the ventrobasal (VB) thalamic complex of rats (n = 42) with a mononeuropathy created 2-3 wk beforehand, by four loose ligatures around the common sciatic nerve. Before the recording session, three behaviora...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.64.5.1537

    authors: Guilbaud G,Benoist JM,Jazat F,Gautron M

    更新日期:1990-11-01 00:00:00

  • Differential modulation of single voltage-gated calcium channels by cholinergic and adrenergic agonists in adult hippocampal neurons.

    abstract::1. Pharmacologic agents known to modulate long-term potentiation (LTP) at the mossy fiber-to-CA3 pyramidal neuron synapse were tested for their effects on the activity of single voltage-gated calcium channels in adult CA3 pyramidal neurons. 2. Single-channel current recordings of three types of voltage-gated calcium c...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.64.4.1291

    authors: Fisher R,Johnston D

    更新日期:1990-10-01 00:00:00

  • Measurement of contractile and electrical properties of single human thenar motor units in response to intraneural motor-axon stimulation.

    abstract::1. A method is described for measuring contractile properties of single human motor units. Conventional human microneurographic techniques were adapted to stimulate individual motor axons in the median nerve, with the use of negative current pulses and a tungsten microelectrode, while recording motor-unit electromyogr...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.64.4.1331

    authors: Westling G,Johansson RS,Thomas CK,Bigland-Ritchie B

    更新日期:1990-10-01 00:00:00

  • Inhibition of sensory responses of cat inferior olive neurons produced by stimulation of red nucleus.

    abstract::1. The sensory responsiveness of cells in the inferior olive is known to be suppressed during certain phases of active movement. These experiments were designed to test the possibility that activity in the rubrospinal pathway contributes to this suppression. We recorded from cells sensitive to light touch located in o...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.64.4.1170

    authors: Weiss C,Houk JC,Gibson AR

    更新日期:1990-10-01 00:00:00

  • Forcing of coupled nonlinear oscillators: studies of intersegmental coordination in the lamprey locomotor central pattern generator.

    abstract::1. This paper reports the results of an investigation of the basic mechanisms underlying intersegmental coordination in lamprey locomotion, by the use of a combined mathematical and biological approach. 2. Mathematically, the lamprey central pattern generator (CPG) is described as a chain of coupled nonlinear oscillat...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.64.3.862

    authors: Williams TL,Sigvardt KA,Kopell N,Ermentrout GB,Remler MP

    更新日期:1990-09-01 00:00:00

  • Identification of histaminergic neurons in Aplysia.

    abstract::1. We have identified putative histaminergic neurons in the central nervous system of Aplysia californica by light-microscopic autoradiography after uptake of [3H]histamine and by immunohistochemistry with the use of an antibody specific for histamine. 2. In the cerebral ganglion cells previously shown to contain hist...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.64.3.736

    authors: Elste A,Koester J,Shapiro E,Panula P,Schwartz JH

    更新日期:1990-09-01 00:00:00

  • Mechanisms of depolarizing inhibition at the crayfish giant motor synapse. I. Electrophysiology.

    abstract::1. Mechanisms of depolarizing synaptic inhibition were investigated at the crayfish giant motor synapse with the use of two-electrode current- and voltage-clamp techniques. Depolarizing inhibitory postsynaptic potentials (d-IPSPs) of between 5 and 15 mV in amplitude are produced there in the motor giant motoneuron (Mo...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.64.2.532

    authors: Edwards DH

    更新日期:1990-08-01 00:00:00

  • Background-induced flicker enhancement in cat retinal horizontal cells. I. Temporal and spectral properties.

    abstract::1. Dim backgrounds can enhance small-spot flicker responses of cat retinal horizontal cells by a factor of 2 or more. 2. Intracellular marking with horseradish peroxidase (HRP) reveals that this enhancement effect occurs in--but is not necessarily limited to--the cone-connected, A-type horizontal cell. 3. Flicker ampl...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.64.2.313

    authors: Pflug R,Nelson R,Ahnelt PK

    更新日期:1990-08-01 00:00:00

  • Postnatal rat nigrostriatal dopaminergic neurons exhibit five types of potassium conductances.

    abstract::1. We have investigated the electrical properties of neurons acutely dissociated from the substantia nigra zona compacta (SNZC) of the postnatal rat with whole cell patch-clamp recordings. Retrogradely labeled nigrostriatal neurons were identified with the use of rhodamine-labeled fluorescent latex microspheres. Over ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.64.1.262

    authors: Silva NL,Pechura CM,Barker JL

    更新日期:1990-07-01 00:00:00

  • Stiffness regulation by reflex action in the normal human hand.

    abstract::1. The torque and electromyographic (EMG) responses to stretch of the first dorsal interosseous muscle (externally imposed joint rotation) were recorded in five normal human subjects. The total measured stiffness was decomposed into three individual stiffness components; passive, intrinsic, and reflex. 2. The passive ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.64.1.105

    authors: Carter RR,Crago PE,Keith MW

    更新日期:1990-07-01 00:00:00

  • Ionic mechanism of substance P actions on neurons in trigeminal root ganglia.

    abstract::1. Responses of primary sensory neurons to substance P applications by perfusion were studied with intracellular recording techniques in in vitro slice preparations of trigeminal root ganglia (guinea pigs). Application of substance P in micromolar doses produced reversible depolarizations of 2-47 mV in 48 out of 64 ne...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.64.1.273

    authors: Spigelman I,Puil E

    更新日期:1990-07-01 00:00:00

  • Temporal correlations in sensory-synaptic interactions: example in crayfish stretch receptors.

    abstract::1. The effects of inhibitory postsynaptic potential (IPSP) barrages on coding of sinusoidal length inputs were investigated in slowly and rapidly adapting stretch receptors of crayfish (RM1 and RM2, respectively). To examine the contribution of postsynaptic firings, a description was obtained of the temporal correlati...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.63.6.1520

    authors: Barrio LC,Buño W

    更新日期:1990-06-01 00:00:00

  • Tactile detection of slip: surface microgeometry and peripheral neural codes.

    abstract::1. The role of the microgeometry of planar surfaces in the detection of sliding of the surfaces on human and monkey fingerpads was investigated. By the use of a servo-controlled tactile stimulator to press and stroke glass plates on passive fingerpads of human subjects, the ability of humans to discriminate the direct...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.63.6.1323

    authors: Srinivasan MA,Whitehouse JM,LaMotte RH

    更新日期:1990-06-01 00:00:00

  • Concentration-jump experiments with NMDA antagonists in mouse cultured hippocampal neurons.

    abstract::1. Voltage-clamp experiments were used to study N-methyl-D-aspartic acid (NMDA) receptor antagonists applied by fast perfusion to mouse hippocampal neurons in dissociated culture. 2. Preincubation with the NMDA antagonists zinc (3-30 microM) and magnesium (30-300 microM) reduced subsequent responses to 100 microM NMDA...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.63.6.1373

    authors: Benveniste M,Mienville JM,Sernagor E,Mayer ML

    更新日期:1990-06-01 00:00:00

  • Receptive-field changes induced by peripheral nerve stimulation in SI of adult cats.

    abstract::1. Receptive fields (RFs) of neurons in the primary somatosensory (SI) cortex were defined before, during, and after electrical stimulation of myelinated fibers in the dorsal cutaneous branch of the ulnar nerve in adult pentobarbital sodium-anesthetized cats. 2. This stimulation resulted in an approximately threefold ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.63.5.1213

    authors: Recanzone GH,Allard TT,Jenkins WM,Merzenich MM

    更新日期:1990-05-01 00:00:00

  • Tonic descending influences on receptive-field properties of nociceptive dorsal horn neurons in sacral spinal cord of rat.

    abstract::1. Single-unit electrical activity has been recorded from 34 dorsal horn neurons in the sacral segments (S1-2) of the spinal cord in halothane-anesthetized rats. All of the neurons had cutaneous receptive fields (RFs) on the rat's tail. The neurons were classified according to their responses to both innocuous and nox...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.63.5.1022

    authors: Laird JM,Cervero F

    更新日期:1990-05-01 00:00:00

  • Proton-gated sodium current in parasympathetic ganglion cells of frog heart.

    abstract::1. The proton-gated current was investigated in whole-cell configuration of the neurons isolated from bullfrog heart parasympathetic ganglia with the use of the "concentration-clamp" technique, which combines intracellular perfusion and extremely rapid exchange of external solution within 1-2 ms, under a single-electr...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.63.5.1060

    authors: Kim DK,Tateishi N,Akaike N

    更新日期:1990-05-01 00:00:00

  • Laminar analysis of extracellular field potentials in rat vibrissa/barrel cortex.

    abstract::1. A 16-channel electrode array was used to record simultaneously extracellular laminar field potentials evoked by displacement of contralateral vibrissa from vibrissa/barrel cortex in five rats. Current source-density (CSD) analysis combined with principal component analysis (PCA) was used to determine the time cours...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.63.4.832

    authors: Di S,Baumgartner C,Barth DS

    更新日期:1990-04-01 00:00:00

  • Responses from parabrachial gustatory neurons in behaving rats.

    abstract::1. The responses of a total of 70 single neurons were recorded from the parabrachial nuclei (PBN) in awake rats. In 59 neurons, sapid stimuli (0.5 ml) elicited significant taste responses. Of these 59 neurons, 10 also had significant responses to water. The mean spontaneous rate of the taste neurons was 13.4 +/- 6.9 (...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.63.4.707

    authors: Nishijo H,Norgren R

    更新日期:1990-04-01 00:00:00

  • Premotor neurons B51 and B52 in the buccal ganglia of Aplysia californica: synaptic connections, effects on ongoing motor rhythms, and peptide modulation.

    abstract::1. Two buccal ganglia interneurons, labeled here as B51 and B52, have been identified on the basis of morphological and physiological criteria. 2. These neurons have multipolar cell bodies. B51 extends a major neurite, which arborizes in the neuropil ipsilateral to the soma; extends into the buccal commissure, where i...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.63.3.539

    authors: Plummer MR,Kirk MD

    更新日期:1990-03-01 00:00:00

  • Recurrent inhibition to and from motoneurons innervating the flexor digitorum and flexor hallucis longus muscles of the cat.

    abstract::1. Recurrent inhibitory postsynaptic potentials (IPSPs) to and from motoneurons innervating the flexor digitorum longus (FDL) and flexor hallucis longus (FHL) muscles of the cat were investigated to determine whether recurrent inhibitory projections involving these motoneurons are similar--as would be consistent with ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.63.3.395

    authors: Hamm TM

    更新日期:1990-03-01 00:00:00

  • Kinesthetic control of a multijoint movement sequence.

    abstract::1. The individual joint rotations of a movement sequence might be controlled either by a central motor plan or by motion-dependent (i.e., kinesthetic) sensory input. Most previous research has focused on how the nervous system uses central motor plans to control movement sequences. This study examined how the nervous ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.63.1.161

    authors: Cordo PJ

    更新日期:1990-01-01 00:00:00

  • N-methyl-D-aspartate receptors of ganglion cells in rabbit retina.

    abstract::1. Intracellular and extracellular recordings were obtained from ganglion cells in the rabbit retina. The effect of N-methyl-DL-aspartate (NMDLA) and N-methyl-D-aspartate (NMDA) antagonists were studied with the use of a perfusion method for drug application. 2. NMDLA excited all ganglion cell types and caused a chara...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1990.63.1.16

    authors: Massey SC,Miller RF

    更新日期:1990-01-01 00:00:00

  • Does an extraocular proprioceptive signal reach the superior colliculus?

    abstract::1. The primary functions of the superior colliculus (SC) are thought to include both the spatial localization of sensory stimuli and the initiation of an orienting response. It has been hypothesized that, in cat, both of these SC functions may be influenced by feedback from the extraocular muscles. The present investi...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1989.62.6.1360

    authors: Nelson JS,Meredith MA,Stein BE

    更新日期:1989-12-01 00:00:00

  • Repetitive firing properties of neurons in the ventral region of nucleus tractus solitarius. In vitro studies in adult and neonatal rat.

    abstract::1. A brain stem slice preparation and intracellular techniques were used to examine the cellular properties of neurons within the ventral and ventrolateral region of the nucleus tractus solitarius (v-NTS) in adult and neonatal (3-12 days old) rats. These neurons are believed to be involved in the control of respirator...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1989.62.6.1213

    authors: Haddad GG,Getting PA

    更新日期:1989-12-01 00:00:00

  • Mechanics of stretch in activated crustacean slow muscle. I. Factors affecting peak force.

    abstract::1. The active stiffness of ventral superficial abdominal muscle (VSM) of the hermit crab, Pagurus pollicarus, was measured with ramp stretches of different amplitudes and velocities. Active stiffness was calculated by subtracting the peak force produced by passive stretch and the isometric force just before stretch fr...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1989.62.5.997

    authors: Chapple WD

    更新日期:1989-11-01 00:00:00

  • Behavioral inspiratory inhibition: inactivated and activated respiratory cells.

    abstract::1. Eleven adult cats were trained to stop inspiration in response to a conditioning stimulus. The conditioning stimuli were presented at the onset of inspiration at intervals of approximately 20-30 s. Intratracheal pressures, diaphragmatic activity, and the extracellular activity of single medullary respiratory neuron...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1989.62.5.1069

    authors: Orem J

    更新日期:1989-11-01 00:00:00

  • Neck muscle spindle activity in the decerebrate, unparalyzed cat: dynamics and influence of vestibular stimulation.

    abstract::1. Using floating electrodes, we recorded from neck-muscle spindle afferents in the C2 dorsal root ganglion of the decerebrate cat. Nerves to dorsal neck muscles were cut so that the afferents presumably originated mainly from ventral and ventrolateral perivertebral muscles and sternocleidomastoid. One goal of our exp...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1989.62.4.917

    authors: Kasper J,Wilson VJ,Yamagata Y,Yates BJ

    更新日期:1989-10-01 00:00:00

  • Errors in pointing are due to approximations in sensorimotor transformations.

    abstract::1. We define an extrinsic frame of reference to represent the location of a point in extrapersonal space relative to a human subject's shoulder, and we define an intrinsic frame of reference to represent the orientation of the arm and forearm. 2. We examined the relations between coordinates in the extrinsic and intri...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1989.62.2.595

    authors: Soechting JF,Flanders M

    更新日期:1989-08-01 00:00:00

  • Responses of monkey medullary dorsal horn neurons during the detection of noxious heat stimuli.

    abstract::1. We examined the activity of thermally sensitive trigeminothalamic neurons and nonprojection neurons in the medullary dorsal horn (trigeminal nucleus caudalis) in three monkeys performing thermal and visual detection tasks. 2. An examination of neuronal stimulus-response functions, obtained during thermal-detection ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1989.62.2.437

    authors: Maixner W,Dubner R,Kenshalo DR Jr,Bushnell MC,Oliveras JL

    更新日期:1989-08-01 00:00:00

  • Kainate receptor-mediated synaptic currents in mudpuppy inner retinal neurons reduced by D-O-phosphoserine.

    abstract::1. The effects of D-O-phosphoserine (DOS) were examined on proximal neurons in the superfused mudpuppy retinal-eyecup preparation by measuring their synaptically evoked whole-cell currents with the use of patch-clamp electrodes. 2. DOS reduced the light-evoked excitatory postsynaptic potentials (EPSPs) of amacrine and...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1989.62.2.495

    authors: Coleman PA,Miller RF

    更新日期:1989-08-01 00:00:00

  • Modulation of pursuit eye movements by stimulation of cortical areas MT and MST.

    abstract::1. Many cells in the superior temporal sulcus (STS) of the monkey that represent the foveal region of the visual field discharge during pursuit eye movements. Damage to these areas produces a deficit in the maintenance of pursuit eye movements when the target towards the side of the brain with the lesion. In the prese...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1989.62.1.31

    authors: Komatsu H,Wurtz RH

    更新日期:1989-07-01 00:00:00

  • Mutable and immutable features of paw-shake responses after hindlimb deafferentation in the cat.

    abstract::1. Hindlimb paw-shake responses were assessed before and after unilateral deafferentation (L3-S1) in chronic-spinal cats (n = 5), spinalized at the T12 level 1 yr earlier. Selected ankle flexor [tibialis anterior (TA)] and extensor [lateral gastrocnemius (LG)] and knee extensor [vastus lateralis (VL)] muscles were sur...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1989.62.1.162

    authors: Koshland GF,Smith JL

    更新日期:1989-07-01 00:00:00

  • Effects of tooth pulp deafferentation on nociceptive and nonnociceptive neurons of the feline trigeminal subnucleus caudalis (medullary dorsal horn).

    abstract::1. Effects of deafferentation of the tooth pulps of the posterior mandibular teeth were studied in single neurons recorded in the ipsilateral subnucleus caudalis of the trigeminal (V) spinal tract nucleus of adult cats and kittens. The functional properties of neurons in each anesthetized animal were determined electr...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1989.61.6.1197

    authors: Hu JW,Sessle BJ

    更新日期:1989-06-01 00:00:00

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